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Title: Exploring Subcellular Cerebellar Fractions with the Electron Microscope
Authors: Triarhou, Lazaros C
Manto, Mario
Type: Article
Subjects: FRASCATI::Medical and Health sciences::Basic medicine
FRASCATI::Natural sciences::Biological sciences
Keywords: Cell organelles
Center for Brain Research
Cerebellar development
Differential ultracentrifugation
Subcellular fractionation
University of Rochester
Subjects MESH: Animals
Cell Fractionation
Subcellular Fractions
Issue Date: Aug-2021
Source: Cerebellum (London, England)
Volume: 20
Issue: 4
First Page: 492
Last Page: 494
Abstract: Differential ultracentrifugation and subcellular fractionation historically helped to study the components of the cell, to discover new cellular organelles, and to decipher their morphological and molecular properties. In neuroscience, the technique has yielded important results on neuron biochemistry and the mechanisms of synaptic transmission. This Cerebellar Classic is devoted to the pioneering work of Manuel del Cerro, Ray S. Snider, and Mary Lou Oster-Granite, who isolated purified fractions after successive centrifugations of the rat cerebellum from birth to adulthood and studied them under the electron microscope.
ISSN: 1473-4222
Electronic ISSN: 1473-4230
Other Identifiers: 10.1007/s12311-021-01286-z
Appears in Collections:Department of Educational & Social Policy

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