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https://ruomo.lib.uom.gr/handle/7000/1432
Τίτλος: | Postnatal Neurogenesis Beyond Rodents: the Groundbreaking Research of Joseph Altman and Gopal Das |
Συγγραφείς: | Triarhou, Lazaros C Manto, Mario |
Τύπος: | Article |
Θέματα: | FRASCATI::Medical and Health sciences::Basic medicine::Neurosciences (including: Psychophysiology) FRASCATI::Natural sciences::Biological sciences |
Λέξεις-Κλειδιά: | Adult neurogenesis Cerebellar development Feline nervous system Granule cells Mitotic divisions |
Θέματα MESH: | Animals Hippocampus Humans Neurons Olfactory Bulb Neurogenesis Rodentia |
Ημερομηνία Έκδοσης: | Φεβ-2022 |
Πηγή: | Cerebellum (London, England) |
Τόμος: | 21 |
Τεύχος: | 1 |
Πρώτη Σελίδα: | 1 |
Τελευταία Σελίδα: | 8 |
Επιτομή: | An integral component of neural ontogeny and plasticity is the ongoing generation of new neurons from precursor cells throughout the lifespan in virtually all animals with a nervous system. In mammals, postnatal neurogenesis has been documented in the cerebellum, olfactory bulb, hippocampus, striatum, substantia nigra, hypothalamus, and amygdala. Germinal centers of new neuron production in the adult brain have been identified in the neuroepithelium of the subventricular zone and the dentate gyrus. One of the earliest lines of evidence gathered came from studies on the production of cerebellar microneurons in the external germinal layer of rodents and carnivores in the 1960s and 1970s. The undeniable pioneer of that research was the insightful developmental neurobiologist Joseph Altman (1925-2016). This Cerebellar Classic is devoted to the groundbreaking work of Altman and his graduate student and, subsequently, fellow faculty member, Gopal Das (1933-1991), on postnatal neurogenesis using tritiated thymidine autoradiography to tag newly formed neurons in the cerebellum of cats. Perseverant to their ideas and patiently working in West Lafayette (Indiana), they were the founders of two fields that brought about paradigm shifts and led to an explosive growth in brain research: adult neurogenesis and neural tissue transplantation. |
URI: | https://doi.org/10.1007/s12311-021-01314-y https://ruomo.lib.uom.gr/handle/7000/1432 |
ISSN: | 1473-4222 1473-4230 |
Ηλεκτρονικό ISSN: | 1473-4230 |
Αλλοι Προσδιοριστές: | 10.1007/s12311-021-01314-y |
Εμφανίζεται στις Συλλογές: | Τμήμα Εκπαιδευτικής & Κοινωνικής Πολιτικής |
Αρχεία σε αυτό το Τεκμήριο:
Αρχείο | Περιγραφή | Μέγεθος | Μορφότυπος | |
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Triarhou Neurogenesis Cerebellum 2022.pdf | Post-print | 110,88 kB | Adobe PDF | Προβολή/Ανοιγμα |
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